Move the box to the wall so you can climb up the tower to the prison cell.
In the cell, take out the letter and fold it. You'll see a Sagittarius and a Scorpio Zodiac Sign. You'll find them on the prison walls. Sagittarius: X, Scorpio II. Those are roman numbers for 10 and 2. Equals 12.
Find the stone with the XII and interact with it.
Climb down to meet Vargas again.
After a fight and talking to Vargas in the Office, escapte the prison by following Sam and Rafe.
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#1 Panamanian Cat Pendant
Climb down the well.